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Rev. chil. reumatol ; 30(4): 148-152, 2014. graf
Article in Spanish | LILACS | ID: lil-776853

ABSTRACT

Rheumatoid Arthritis (RA) is characterized by persistent synovitis, systemic inflammation and presence of autoantibodies, mainly Rheumatoid Factor and Anticitrullinated peptide antibody. This condition develop in genetically susceptible individuals, where environmental factors interact, although the pathogenesis is not yet fully known. Since the disease was described until now, there have been major diagnostic and therapeutic advances. In this paper was performed a retrospective and prospective evaluation of 28 patients with RA over twenty years of evolution, was held in treatment and periodic inspection at the Department of Rheumatology at Hospital San Juan de Dios...


La Artritis Reumatoide (AR) se caracteriza por presentar una sinovitis persistente, inflamación sistémica y presencia de autoanticuerpos, fundamentalmente factor reumatoideo y anticuerpo anti-péptido citrulinado. Esta patología se desarrolla en individuos genéticamente susceptibles, donde interactúan diversos factores ambientales, aunque la patogenia aún no se conoce en su totalidad. Desde que se describió la enfermedad hasta la actualidad, ha habido grandes avances diagnósticos y terapéuticos. En este trabajo se realizó una evaluación retrospectiva y prospectiva de 28 pacientes con AR sobre 20 años de evolución, en tratamiento y control periódico en el Departamento de Reumatología del Hospital San Juan de Dios...


Subject(s)
Humans , Male , Adult , Female , Middle Aged , Aged, 80 and over , Antirheumatic Agents/therapeutic use , Arthritis, Rheumatoid/drug therapy , Clinical Evolution , Prospective Studies , Retrospective Studies
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